This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5mv8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:51, 8 November 2023) (edit) (undo)
 
Line 1: Line 1:
==Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain==
==Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain==
-
<StructureSection load='5mv8' size='340' side='right' caption='[[5mv8]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
+
<StructureSection load='5mv8' size='340' side='right'caption='[[5mv8]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5mv8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MV8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MV8 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5mv8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MV8 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYO7B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mv8 OCA], [http://pdbe.org/5mv8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mv8 RCSB], [http://www.ebi.ac.uk/pdbsum/5mv8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mv8 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mv8 OCA], [https://pdbe.org/5mv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mv8 RCSB], [https://www.ebi.ac.uk/pdbsum/5mv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mv8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/MYO7B_HUMAN MYO7B_HUMAN]] Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli (Probable).<ref>PMID:24725409</ref> <ref>PMID:26812018</ref>
+
[https://www.uniprot.org/uniprot/MYO7B_HUMAN MYO7B_HUMAN] Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli (Probable).<ref>PMID:24725409</ref> <ref>PMID:26812018</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 5mv8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5mv8" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Harmonin|Harmonin]]
 +
*[[Myosin 3D Structures|Myosin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Houdusse, A]]
+
[[Category: Large Structures]]
-
[[Category: Sourigues, Y]]
+
[[Category: Houdusse A]]
-
[[Category: Titus, M A]]
+
[[Category: Sourigues Y]]
-
[[Category: Yu, I]]
+
[[Category: Titus MA]]
-
[[Category: Harmonin]]
+
[[Category: Yu I]]
-
[[Category: Motor protein]]
+
-
[[Category: Myosin]]
+
-
[[Category: Myosin tail]]
+
-
[[Category: Pdz]]
+

Current revision

Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain

PDB ID 5mv8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5mv8"
Personal tools