2ckz

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==X-ray structure of RNA polymerase III subcomplex C17-C25.==
==X-ray structure of RNA polymerase III subcomplex C17-C25.==
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<StructureSection load='2ckz' size='340' side='right' caption='[[2ckz]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='2ckz' size='340' side='right'caption='[[2ckz]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ckz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CKZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ckz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CKZ FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ckz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ckz OCA], [http://pdbe.org/2ckz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ckz RCSB], [http://www.ebi.ac.uk/pdbsum/2ckz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ckz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ckz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ckz OCA], [https://pdbe.org/2ckz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ckz RCSB], [https://www.ebi.ac.uk/pdbsum/2ckz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ckz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RPC9_YEAST RPC9_YEAST]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation. [[http://www.uniprot.org/uniprot/RPC8_YEAST RPC8_YEAST]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNA. The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation.
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[https://www.uniprot.org/uniprot/RPC9_YEAST RPC9_YEAST] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/2ckz_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/2ckz_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2ckz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2ckz" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
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[[Category: DNA-directed RNA polymerase]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Armache, K J]]
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[[Category: Armache K-J]]
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[[Category: Cramer, P]]
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[[Category: Cramer P]]
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[[Category: Jansen, R P]]
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[[Category: Jansen R-P]]
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[[Category: Jasiak, A J]]
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[[Category: Jasiak AJ]]
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[[Category: Martens, B]]
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[[Category: Martens B]]
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[[Category: Class iii gene transcription]]
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[[Category: Dna-directed rna polymerase]]
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[[Category: Eukaryotic nucleic acid polymerase]]
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[[Category: Hypothetical protein]]
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[[Category: Multiprotein complex]]
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[[Category: Nuclear protein]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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[[Category: Trna synthesis]]
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Current revision

X-ray structure of RNA polymerase III subcomplex C17-C25.

PDB ID 2ckz

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