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5nzx
From Proteopedia
(Difference between revisions)
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==Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)== | ==Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)== | ||
| - | <StructureSection load='5nzx' size='340' side='right' caption='[[5nzx]], [[Resolution|resolution]] 1.47Å' scene=''> | + | <StructureSection load='5nzx' size='340' side='right'caption='[[5nzx]], [[Resolution|resolution]] 1.47Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5nzx]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5nzx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NZX FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9F2:Ceftriaxone'>9F2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzx OCA], [https://pdbe.org/5nzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nzx RCSB], [https://www.ebi.ac.uk/pdbsum/5nzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzx ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Aitkenhead | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Aitkenhead H]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Burgess-Brown | + | [[Category: Bountra C]] |
| - | + | [[Category: Burgess-Brown NA]] | |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Gileadi | + | [[Category: Gileadi O]] |
| - | [[Category: Krojer | + | [[Category: Krojer T]] |
| - | [[Category: Kupinska | + | [[Category: Kupinska K]] |
| - | [[Category: Newman | + | [[Category: Newman JA]] |
| - | [[Category: Talon | + | [[Category: Talon R]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
| - | + | ||
| - | + | ||
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Current revision
Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)
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Categories: Homo sapiens | Large Structures | Aitkenhead H | Arrowsmith CH | Bountra C | Burgess-Brown NA | Edwards A | Gileadi O | Krojer T | Kupinska K | Newman JA | Talon R | Von Delft F
