2b7p

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[[Image:2b7p.gif|left|200px]]
 
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{{Structure
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==Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori with phthalic acid==
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|PDB= 2b7p |SIZE=350|CAPTION= <scene name='initialview01'>2b7p</scene>, resolution 2.51&Aring;
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<StructureSection load='2b7p' size='340' side='right'caption='[[2b7p]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=PHT:PHTHALIC+ACID'>PHT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[2b7p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B7P FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Nicotinate-nucleotide_diphosphorylase_(carboxylating) Nicotinate-nucleotide diphosphorylase (carboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.19 2.4.2.19] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PHT:PHTHALIC+ACID'>PHT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b7p OCA], [https://pdbe.org/2b7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b7p RCSB], [https://www.ebi.ac.uk/pdbsum/2b7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b7p ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b7p OCA], [http://www.ebi.ac.uk/pdbsum/2b7p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2b7p RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/NADC_HELPY NADC_HELPY] Involved in the catabolism of quinolinic acid (QA) (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/2b7p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b7p ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori'''
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2B7P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7P OCA].
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==Reference==
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Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori., Kim MK, Im YJ, Lee JH, Eom SH, Proteins. 2006 Apr 1;63(1):252-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16419067 16419067]
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[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Nicotinate-nucleotide diphosphorylase (carboxylating)]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Eom SH]]
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[[Category: Eom, S H.]]
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[[Category: Im YJ]]
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[[Category: Im, Y J.]]
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[[Category: Kim MK]]
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[[Category: Kim, M K.]]
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[[Category: Lee JH]]
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[[Category: Lee, J H.]]
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[[Category: helicobacter pylori]]
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[[Category: quinolinate phosphoribosyltransferase]]
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[[Category: quinolinic acid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:02:34 2008''
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Current revision

Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori with phthalic acid

PDB ID 2b7p

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