4y64

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==AAGlyB in complex with amino-acid analogues==
==AAGlyB in complex with amino-acid analogues==
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<StructureSection load='4y64' size='340' side='right' caption='[[4y64]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4y64' size='340' side='right'caption='[[4y64]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4y64]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y64 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4y64]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y64 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48C:5-(D-ALANYLAMINO)-5-DEOXYURIDINE'>48C</scene>, <scene name='pdbligand=BHE:OCTYL+2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE'>BHE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=48C:5-(D-ALANYLAMINO)-5-DEOXYURIDINE'>48C</scene>, <scene name='pdbligand=BHE:OCTYL+2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE'>BHE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y64 OCA], [http://pdbe.org/4y64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y64 RCSB], [http://www.ebi.ac.uk/pdbsum/4y64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y64 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y64 OCA], [https://pdbe.org/4y64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y64 RCSB], [https://www.ebi.ac.uk/pdbsum/4y64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y64 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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==See Also==
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Cuesta-Seijo, J A]]
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[[Category: Large Structures]]
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[[Category: Lafont, D]]
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[[Category: Cuesta-Seijo JA]]
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[[Category: Palcic, M M]]
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[[Category: Lafont D]]
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[[Category: Striebeck, A]]
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[[Category: Palcic MM]]
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[[Category: Vidal, S]]
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[[Category: Striebeck A]]
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[[Category: Wang, S]]
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[[Category: Vidal S]]
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[[Category: Inhibitor]]
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[[Category: Wang S]]
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[[Category: Transferase]]
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AAGlyB in complex with amino-acid analogues

PDB ID 4y64

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