This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6f00
From Proteopedia
(Difference between revisions)
m (Protected "6f00" [edit=sysop:move=sysop]) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human tRNA dihydrouridine synthase (20) dsRBD E423A mutant== | |
| - | + | <StructureSection load='6f00' size='340' side='right' caption='[[6f00]], [[Resolution|resolution]] 2.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6f00]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F00 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f00 OCA], [http://pdbe.org/6f00 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f00 RCSB], [http://www.ebi.ac.uk/pdbsum/6f00 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f00 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DUS2L_HUMAN DUS2L_HUMAN]] Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.<ref>PMID:15994936</ref> <ref>PMID:18096616</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Charles, B N]] | ||
[[Category: Djemel, H]] | [[Category: Djemel, H]] | ||
| - | [[Category: | + | [[Category: Double-stranded rna binding domain]] |
| + | [[Category: Rna binding protein]] | ||
Current revision
Crystal Structure of human tRNA dihydrouridine synthase (20) dsRBD E423A mutant
| |||||||||||
