3mnq

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==Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol==
==Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol==
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<StructureSection load='3mnq' size='340' side='right' caption='[[3mnq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3mnq' size='340' side='right'caption='[[3mnq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mnq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum_ax4 Dictyostelium discoideum ax4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MNQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MNQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mnq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum_AX4 Dictyostelium discoideum AX4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MNQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=STL:RESVERATROL'>STL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jhr|2jhr]], [[2jj9|2jj9]], [[1fmv|1fmv]], [[1fmw|1fmw]], [[1mma|1mma]], [[1mmd|1mmd]], [[1mmg|1mmg]], [[1mmn|1mmn]], [[1mnd|1mnd]], [[1vom|1vom]], [[1w9i|1w9i]], [[1w9j|1w9j]], [[1yv3|1yv3]], [[3fts|3fts]], [[3ftu|3ftu]], [[3ckl|3ckl]], [[2jiz|2jiz]], [[1z1f|1z1f]], [[1sg0|1sg0]], [[1u0w|1u0w]], [[1dvs|1dvs]], [[1cgz|1cgz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=STL:RESVERATROL'>STL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mhcA, DDB_G0286355 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=352472 Dictyostelium discoideum AX4])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mnq OCA], [https://pdbe.org/3mnq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mnq RCSB], [https://www.ebi.ac.uk/pdbsum/3mnq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mnq ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mnq OCA], [http://pdbe.org/3mnq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mnq RCSB], [http://www.ebi.ac.uk/pdbsum/3mnq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mnq ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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==See Also==
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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*[[Myosin 3D Structures|Myosin 3D Structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dictyostelium discoideum ax4]]
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[[Category: Dictyostelium discoideum AX4]]
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[[Category: Myosin ATPase]]
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[[Category: Large Structures]]
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[[Category: Backhaus, A]]
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[[Category: Backhaus A]]
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[[Category: Baruch, P]]
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[[Category: Baruch P]]
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[[Category: Fedorov, R]]
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[[Category: Fedorov R]]
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[[Category: Manstein, D J]]
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[[Category: Manstein DJ]]
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[[Category: Schneider, J]]
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[[Category: Schneider J]]
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[[Category: Taft, M]]
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[[Category: Taft M]]
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[[Category: Actin-binding]]
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[[Category: Activator]]
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[[Category: Allosteric]]
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[[Category: Atp-binding]]
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[[Category: Calmodulin-binding]]
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[[Category: Contractile protein]]
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[[Category: Inhibitor]]
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[[Category: Motor domain]]
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[[Category: Motor protein]]
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[[Category: Motor protein-inhibitor complex]]
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[[Category: Myosin]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Resveratrol]]
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Current revision

Crystal structure of myosin-2 motor domain in complex with ADP-metavanadate and resveratrol

PDB ID 3mnq

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