4nyn
From Proteopedia
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==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1== | ==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1== | ||
| - | <StructureSection load='4nyn' size='340' side='right' caption='[[4nyn]], [[Resolution|resolution]] 1.41Å' scene=''> | + | <StructureSection load='4nyn' size='340' side='right'caption='[[4nyn]], [[Resolution|resolution]] 1.41Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nyn]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4nyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum_NRC-1 Halobacterium salinarum NRC-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NYN FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nyn OCA], [https://pdbe.org/4nyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nyn RCSB], [https://www.ebi.ac.uk/pdbsum/4nyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nyn ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref> |
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Halobacterium salinarum NRC-1]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Angkawidjaja | + | [[Category: Angkawidjaja C]] |
| - | [[Category: Kanaya | + | [[Category: Kanaya S]] |
| - | [[Category: Koga | + | [[Category: Koga Y]] |
| - | [[Category: You | + | [[Category: You DJ]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
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