This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4pim

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:44, 28 December 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Ergothioneine-biosynthetic methyltransferase EgtD, apo form==
==Ergothioneine-biosynthetic methyltransferase EgtD, apo form==
-
<StructureSection load='4pim' size='340' side='right' caption='[[4pim]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
+
<StructureSection load='4pim' size='340' side='right'caption='[[4pim]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4pim]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_smegmatis"_trevisan_1889 "bacillus smegmatis" trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PIM FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4pim]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PIM FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pin|4pin]], [[4pio|4pio]], [[4pip|4pip]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pim OCA], [https://pdbe.org/4pim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pim RCSB], [https://www.ebi.ac.uk/pdbsum/4pim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pim ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">egtD, MSMEG_6247, MSMEI_6086 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1772 "Bacillus smegmatis" Trevisan 1889])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-histidine_N(alpha)-methyltransferase L-histidine N(alpha)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.44 2.1.1.44] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pim OCA], [http://pdbe.org/4pim PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pim RCSB], [http://www.ebi.ac.uk/pdbsum/4pim PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pim ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/EGTD_MYCS2 EGTD_MYCS2]] Catalyzes the methylations of histidine to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine). Histidine and alpha-N,N-dimethylhistidine are preferred substrates.<ref>PMID:20420449</ref>
+
[https://www.uniprot.org/uniprot/EGTD_MYCS2 EGTD_MYCS2] Catalyzes the methylations of histidine to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine). Histidine and alpha-N,N-dimethylhistidine are preferred substrates.<ref>PMID:20420449</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacillus smegmatis trevisan 1889]]
+
[[Category: Large Structures]]
-
[[Category: Blankenfeldt, W]]
+
[[Category: Mycolicibacterium smegmatis]]
-
[[Category: Seebeck, F P]]
+
[[Category: Blankenfeldt W]]
-
[[Category: Vit, A]]
+
[[Category: Seebeck FP]]
-
[[Category: Ergothioneine]]
+
[[Category: Vit A]]
-
[[Category: Histidine betaine]]
+
-
[[Category: Methyltransferase]]
+
-
[[Category: Transferase]]
+

Current revision

Ergothioneine-biosynthetic methyltransferase EgtD, apo form

PDB ID 4pim

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4pim"
Personal tools