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4q10

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==The catalytic core of Rad2 in complex with DNA substrate (complex IV)==
==The catalytic core of Rad2 in complex with DNA substrate (complex IV)==
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<StructureSection load='4q10' size='340' side='right' caption='[[4q10]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='4q10' size='340' side='right'caption='[[4q10]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4q10]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q10 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q10 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4q10]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q10 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q0w|4q0w]], [[4q0z|4q0z]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAD2, YGR258C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q10 OCA], [https://pdbe.org/4q10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q10 RCSB], [https://www.ebi.ac.uk/pdbsum/4q10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q10 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q10 OCA], [http://pdbe.org/4q10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q10 RCSB], [http://www.ebi.ac.uk/pdbsum/4q10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q10 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAD2_YEAST RAD2_YEAST]] Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.<ref>PMID:8247134</ref>
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[https://www.uniprot.org/uniprot/RAD2_YEAST RAD2_YEAST] Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.<ref>PMID:8247134</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
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[[Category: Large Structures]]
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[[Category: Jaciuk, M]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Kustosz, P]]
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[[Category: Jaciuk M]]
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[[Category: Mietus, M]]
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[[Category: Kustosz P]]
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[[Category: Nowak, E]]
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[[Category: Mietus M]]
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[[Category: Nowotny, M]]
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[[Category: Nowak E]]
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[[Category: Ba rossmann-like]]
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[[Category: Nowotny M]]
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[[Category: Dna repair]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Nucleus]]
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[[Category: Tfiih]]
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Current revision

The catalytic core of Rad2 in complex with DNA substrate (complex IV)

PDB ID 4q10

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