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4rxx

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==Crystal Structure of the N-terminal Domain of Human Ubiquitin Specific Protease 38==
==Crystal Structure of the N-terminal Domain of Human Ubiquitin Specific Protease 38==
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<StructureSection load='4rxx' size='340' side='right' caption='[[4rxx]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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<StructureSection load='4rxx' size='340' side='right'caption='[[4rxx]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rxx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RXX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rxx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RXX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxx OCA], [https://pdbe.org/4rxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rxx RCSB], [https://www.ebi.ac.uk/pdbsum/4rxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxx ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">USP38, KIAA1891 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitinyl_hydrolase_1 Ubiquitinyl hydrolase 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.12 3.4.19.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rxx OCA], [http://pdbe.org/4rxx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rxx RCSB], [http://www.ebi.ac.uk/pdbsum/4rxx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rxx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UBP38_HUMAN UBP38_HUMAN]] Deubiquitinating enzyme exhibiting a preference towards 'Lys-63'-linked Ubiquitin chains.<ref>PMID:22689415</ref>
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[https://www.uniprot.org/uniprot/UBP38_HUMAN UBP38_HUMAN] Deubiquitinating enzyme exhibiting a preference towards 'Lys-63'-linked Ubiquitin chains.<ref>PMID:22689415</ref>
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==See Also==
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*[[Thioesterase 3D structures|Thioesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Ubiquitinyl hydrolase 1]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Dong, A]]
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[[Category: Dong A]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Hu, J]]
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[[Category: Hu J]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Structural genomic]]
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[[Category: Shen L]]
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[[Category: Shen, L]]
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[[Category: Tempel W]]
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[[Category: Tempel, W]]
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[[Category: Tong Y]]
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[[Category: Tong, Y]]
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[[Category: Heat-repeat]]
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[[Category: Hydrolase]]
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[[Category: Sgc]]
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[[Category: Ubiquitin-specific protease]]
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Current revision

Crystal Structure of the N-terminal Domain of Human Ubiquitin Specific Protease 38

PDB ID 4rxx

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