5dj9

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==Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with gabaculine==
==Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with gabaculine==
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<StructureSection load='5dj9' size='340' side='right' caption='[[5dj9]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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<StructureSection load='5dj9' size='340' side='right'caption='[[5dj9]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dj9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgm Toxgm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DJ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DJ9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii_ME49 Toxoplasma gondii ME49]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DJ9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=PXG:3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC+ACID'>PXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zwm|4zwm]], [[4zlv|4zlv]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=PXG:3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC+ACID'>PXG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGME49_269110 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=508771 TOXGM])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dj9 OCA], [https://pdbe.org/5dj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dj9 RCSB], [https://www.ebi.ac.uk/pdbsum/5dj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dj9 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_aminotransferase Ornithine aminotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.13 2.6.1.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dj9 OCA], [http://pdbe.org/5dj9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dj9 RCSB], [http://www.ebi.ac.uk/pdbsum/5dj9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dj9 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S8EY38_TOXGM S8EY38_TOXGM]
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==See Also==
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*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ornithine aminotransferase]]
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[[Category: Large Structures]]
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[[Category: Toxgm]]
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[[Category: Toxoplasma gondii ME49]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Filippova EV]]
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[[Category: Filippova, E V]]
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[[Category: Flores K]]
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[[Category: Flores, K]]
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[[Category: Le HV]]
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[[Category: Le, H V]]
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[[Category: McLeod RL]]
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[[Category: McLeod, R L]]
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[[Category: Minasov G]]
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[[Category: Minasov, G]]
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[[Category: Silverman RB]]
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[[Category: Silverman, R B]]
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[[Category: Complex]]
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[[Category: Csgid]]
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[[Category: Inhibitor]]
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[[Category: Parasite]]
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[[Category: Pyridoxal 5'-phosphate]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with gabaculine

PDB ID 5dj9

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