5eu9
From Proteopedia
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| ==Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid== | ==Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid== | ||
| - | <StructureSection load='5eu9' size='340' side='right' caption='[[5eu9]], [[Resolution|resolution]] 2.05Å' scene=''> | + | <StructureSection load='5eu9' size='340' side='right'caption='[[5eu9]], [[Resolution|resolution]] 2.05Å' scene=''> | 
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5eu9]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5eu9]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EU9 FirstGlance]. <br> | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5TX:((3S,5S)-1,5-DIHYDROXY-3-METHYL-2-OXOPYRROLIDIN-3-YL)PHOSPHONIC+ACID'>5TX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.047Å</td></tr> | 
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5TX:((3S,5S)-1,5-DIHYDROXY-3-METHYL-2-OXOPYRROLIDIN-3-YL)PHOSPHONIC+ACID'>5TX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eu9 OCA], [https://pdbe.org/5eu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eu9 RCSB], [https://www.ebi.ac.uk/pdbsum/5eu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eu9 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
| </table> | </table> | ||
| == Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ENOG_HUMAN ENOG_HUMAN] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). | 
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| + | ==See Also== | ||
| + | *[[Enolase 3D structures|Enolase 3D structures]] | ||
| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| - | [[Category:  | + | [[Category: Homo sapiens]] | 
| - | [[Category:  | + | [[Category: Large Structures]] | 
| - | [[Category: Leonard | + | [[Category: Leonard PG]] | 
| - | [[Category: Muller | + | [[Category: Muller FL]] | 
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Current revision
Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid
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