5u32
From Proteopedia
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==Crystal Structure of Fungal RNA Kinase== | ==Crystal Structure of Fungal RNA Kinase== | ||
- | <StructureSection load='5u32' size='340' side='right' caption='[[5u32]], [[Resolution|resolution]] 2.19Å' scene=''> | + | <StructureSection load='5u32' size='340' side='right'caption='[[5u32]], [[Resolution|resolution]] 2.19Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[5u32]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5u32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U32 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.191Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u32 OCA], [https://pdbe.org/5u32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u32 RCSB], [https://www.ebi.ac.uk/pdbsum/5u32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u32 ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/TRNL_CANAL TRNL_CANAL] One of the two proteins required for the splicing of precursor tRNA molecules containing introns. The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Candida albicans SC5314]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Goldgur Y]] |
- | [[Category: | + | [[Category: Remus BS]] |
- | [[Category: | + | [[Category: Shuman S]] |
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Current revision
Crystal Structure of Fungal RNA Kinase
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