5u32

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==Crystal Structure of Fungal RNA Kinase==
==Crystal Structure of Fungal RNA Kinase==
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<StructureSection load='5u32' size='340' side='right' caption='[[5u32]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
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<StructureSection load='5u32' size='340' side='right'caption='[[5u32]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5u32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canal Canal]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U32 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5u32]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U32 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U32 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.191&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LIG1, RLG1, TRL1, CAALFM_C702060WA, CaJ7.0238, CaO19.13864, CaO19.6511 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237561 CANAL])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_ligase_(ATP) RNA ligase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.3 6.5.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u32 OCA], [https://pdbe.org/5u32 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u32 RCSB], [https://www.ebi.ac.uk/pdbsum/5u32 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u32 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u32 OCA], [http://pdbe.org/5u32 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u32 RCSB], [http://www.ebi.ac.uk/pdbsum/5u32 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u32 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRNL_CANAL TRNL_CANAL] One of the two proteins required for the splicing of precursor tRNA molecules containing introns. The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Canal]]
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[[Category: Candida albicans SC5314]]
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[[Category: Goldgur, Y]]
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[[Category: Large Structures]]
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[[Category: Remus, B S]]
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[[Category: Goldgur Y]]
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[[Category: Shuman, S]]
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[[Category: Remus BS]]
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[[Category: Polynucleotide kinase]]
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[[Category: Shuman S]]
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[[Category: Rna ligase]]
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[[Category: Rna repair]]
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[[Category: Transferase]]
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Crystal Structure of Fungal RNA Kinase

PDB ID 5u32

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