This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6axa
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with (3S)-5-fluoro-3-hydroxy-1,3-dihydroindol-2-one== | |
| + | <StructureSection load='6axa' size='340' side='right'caption='[[6axa]], [[Resolution|resolution]] 1.59Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6axa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AXA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=D4Y:(3S)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one'>D4Y</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6axa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6axa OCA], [https://pdbe.org/6axa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6axa RCSB], [https://www.ebi.ac.uk/pdbsum/6axa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6axa ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477] | ||
| - | + | ==See Also== | |
| - | + | *[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Schistosoma mansoni]] |
| - | [[Category: | + | [[Category: Barbosa JARG]] |
| - | [[Category: Delft | + | [[Category: Bird L]] |
| - | [[Category: | + | [[Category: Collins P]] |
| - | [[Category: Neto | + | [[Category: Delft FV]] |
| - | [[Category: | + | [[Category: Faheem M]] |
| - | [[Category: | + | [[Category: Neto JB]] |
| - | [[Category: | + | [[Category: Pearce NM]] |
| + | [[Category: Pereira HM]] | ||
| + | [[Category: Valadares NF]] | ||
Current revision
Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with (3S)-5-fluoro-3-hydroxy-1,3-dihydroindol-2-one
| |||||||||||
Categories: Large Structures | Schistosoma mansoni | Barbosa JARG | Bird L | Collins P | Delft FV | Faheem M | Neto JB | Pearce NM | Pereira HM | Valadares NF
