6bp7

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(New page: '''Unreleased structure''' The entry 6bp7 is ON HOLD Authors: Ding, K., Zhang, X., Mrazek, J., Kickhoefer, V.A., Lai, M., Ng, H.L., Yang, O.O., Rome, L.H., Zhou, Z.H. Description: Reco...)
Current revision (14:23, 13 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6bp7 is ON HOLD
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==Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 2==
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<SX load='6bp7' size='340' side='right' viewer='molstar' caption='[[6bp7]], [[Resolution|resolution]] 4.90&Aring;' scene=''>
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Authors: Ding, K., Zhang, X., Mrazek, J., Kickhoefer, V.A., Lai, M., Ng, H.L., Yang, O.O., Rome, L.H., Zhou, Z.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bp7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BP7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BP7 FirstGlance]. <br>
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Description: Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 2
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.9&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bp7 OCA], [https://pdbe.org/6bp7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bp7 RCSB], [https://www.ebi.ac.uk/pdbsum/6bp7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bp7 ProSAT]</span></td></tr>
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[[Category: Lai, M]]
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</table>
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[[Category: Zhou, Z.H]]
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== Function ==
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[[Category: Ding, K]]
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[https://www.uniprot.org/uniprot/MVP_RAT MVP_RAT] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).
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[[Category: Kickhoefer, V.A]]
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__TOC__
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[[Category: Mrazek, J]]
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</SX>
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[[Category: Rome, L.H]]
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[[Category: Large Structures]]
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[[Category: Yang, O.O]]
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[[Category: Rattus norvegicus]]
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[[Category: Ng, H.L]]
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[[Category: Ding K]]
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[[Category: Zhang, X]]
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[[Category: Kickhoefer VA]]
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[[Category: Lai M]]
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[[Category: Mrazek J]]
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[[Category: Ng HL]]
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[[Category: Rome LH]]
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[[Category: Yang OO]]
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[[Category: Zhang X]]
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[[Category: Zhou ZH]]

Current revision

Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 2

6bp7, resolution 4.90Å

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