6f00
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human tRNA dihydrouridine synthase (20) dsRBD E423A mutant== | |
| - | + | <StructureSection load='6f00' size='340' side='right' caption='[[6f00]], [[Resolution|resolution]] 2.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6f00]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F00 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f00 OCA], [http://pdbe.org/6f00 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f00 RCSB], [http://www.ebi.ac.uk/pdbsum/6f00 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f00 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DUS2L_HUMAN DUS2L_HUMAN]] Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.<ref>PMID:15994936</ref> <ref>PMID:18096616</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Charles, B N]] | ||
[[Category: Djemel, H]] | [[Category: Djemel, H]] | ||
| - | [[Category: | + | [[Category: Double-stranded rna binding domain]] |
| + | [[Category: Rna binding protein]] | ||
Current revision
Crystal Structure of human tRNA dihydrouridine synthase (20) dsRBD E423A mutant
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