2bru

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[[Image:2bru.gif|left|200px]]
 
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{{Structure
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==Complex of the domain I and domain III of Escherichia coli transhydrogenase==
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|PDB= 2bru |SIZE=350|CAPTION= <scene name='initialview01'>2bru</scene>
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<StructureSection load='2bru' size='340' side='right'caption='[[2bru]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>
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<table><tr><td colspan='2'>[[2bru]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BRU FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)(+)_transhydrogenase_(AB-specific) NAD(P)(+) transhydrogenase (AB-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.1.2 1.6.1.2] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bru OCA], [https://pdbe.org/2bru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bru RCSB], [https://www.ebi.ac.uk/pdbsum/2bru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bru ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bru OCA], [http://www.ebi.ac.uk/pdbsum/2bru PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2bru RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PNTA_ECOLI PNTA_ECOLI] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2bru_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bru ConSurf].
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<div style="clear:both"></div>
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'''COMPLEX OF THE DOMAIN I AND DOMAIN III OF ESCHERICHIA COLI TRANSHYDROGENASE'''
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==See Also==
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*[[NAD(P) transhydrogenase 3D structures|NAD(P) transhydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2BRU is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRU OCA].
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: NAD(P)(+) transhydrogenase (AB-specific)]]
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[[Category: Large Structures]]
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[[Category: Protein complex]]
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[[Category: Johansson T]]
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[[Category: Johansson, T.]]
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[[Category: Karlsson BG]]
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[[Category: Karlsson, B G.]]
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[[Category: Leckner J]]
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[[Category: Leckner, J.]]
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[[Category: Pedersen A]]
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[[Category: Pedersen, A.]]
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[[Category: inner membrane]]
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[[Category: membrane]]
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[[Category: nad]]
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[[Category: nadp]]
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[[Category: oxidoreductase]]
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[[Category: paramagnetic nmr]]
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[[Category: transhydrogenase]]
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[[Category: transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:10:53 2008''
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Current revision

Complex of the domain I and domain III of Escherichia coli transhydrogenase

PDB ID 2bru

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