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1uh5

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==Crystal Structure of Enoyl-ACP Reductase with Triclosan at 2.2angstroms==
==Crystal Structure of Enoyl-ACP Reductase with Triclosan at 2.2angstroms==
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<StructureSection load='1uh5' size='340' side='right' caption='[[1uh5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1uh5' size='340' side='right'caption='[[1uh5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uh5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UH5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UH5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uh5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UH5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCL:TRICLOSAN'>TCL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1eno|1eno]], [[1nhg|1nhg]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCL:TRICLOSAN'>TCL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FabI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uh5 OCA], [https://pdbe.org/1uh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uh5 RCSB], [https://www.ebi.ac.uk/pdbsum/1uh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uh5 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uh5 OCA], [http://pdbe.org/1uh5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uh5 RCSB], [http://www.ebi.ac.uk/pdbsum/1uh5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uh5 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9BJJ9_PLAFA Q9BJJ9_PLAFA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uh/1uh5_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uh/1uh5_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1uh5" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1uh5" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Plafa]]
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[[Category: Large Structures]]
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[[Category: Kapoor, M]]
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[[Category: Plasmodium falciparum]]
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[[Category: Suguna, K]]
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[[Category: Kapoor M]]
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[[Category: Surolia, A]]
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[[Category: Suguna K]]
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[[Category: Surolia, N]]
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[[Category: Surolia A]]
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[[Category: Swarnamukhi, P L]]
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[[Category: Surolia N]]
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[[Category: Enoyl-acp reductase]]
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[[Category: Swarnamukhi PL]]
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[[Category: Fabi]]
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[[Category: Nad+]]
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[[Category: Oxidoreductase]]
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[[Category: P falciparum]]
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[[Category: Triclosan]]
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Current revision

Crystal Structure of Enoyl-ACP Reductase with Triclosan at 2.2angstroms

PDB ID 1uh5

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OCA

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