3omu

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==Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a thienopyrimidine derivative==
==Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a thienopyrimidine derivative==
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<StructureSection load='3omu' size='340' side='right' caption='[[3omu]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='3omu' size='340' side='right'caption='[[3omu]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3omu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OMU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OMU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3omu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OMU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IBD:2-AMINO-4-{2,4-DICHLORO-5-[2-(DIETHYLAMINO)ETHOXY]PHENYL}-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE'>IBD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o6o|3o6o]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IBD:2-AMINO-4-{2,4-DICHLORO-5-[2-(DIETHYLAMINO)ETHOXY]PHENYL}-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE'>IBD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb10.26.1080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma (Trypanozoon) brucei])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3omu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3omu OCA], [https://pdbe.org/3omu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3omu RCSB], [https://www.ebi.ac.uk/pdbsum/3omu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3omu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3omu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3omu OCA], [http://pdbe.org/3omu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3omu RCSB], [http://www.ebi.ac.uk/pdbsum/3omu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3omu ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q389P1_TRYB2 Q389P1_TRYB2]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3omu" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3omu" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A]]
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[[Category: Trypanosoma brucei]]
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[[Category: Bountra, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Cossar, D]]
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[[Category: Bochkarev A]]
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[[Category: Edwards, A M]]
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[[Category: Bountra C]]
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[[Category: Fairlamb, A H]]
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[[Category: Cossar D]]
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[[Category: Ferguson, M A.J]]
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[[Category: Edwards AM]]
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[[Category: Hills, T]]
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[[Category: Fairlamb AH]]
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[[Category: Hui, R]]
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[[Category: Ferguson MAJ]]
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[[Category: Hutchinson, A]]
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[[Category: Hills T]]
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[[Category: Kozieradzki, I]]
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[[Category: Hui R]]
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[[Category: Li, Y]]
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[[Category: Hutchinson A]]
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[[Category: MacKenzie, C]]
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[[Category: Kozieradzki I]]
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[[Category: Pizarro, J C]]
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[[Category: Li Y]]
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[[Category: Structural genomic]]
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[[Category: MacKenzie C]]
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[[Category: Sullivan, H]]
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[[Category: Pizarro JC]]
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[[Category: Weadge, J]]
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[[Category: Sullivan H]]
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[[Category: Weigelt, J]]
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[[Category: Weadge J]]
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[[Category: Wernimont, A K]]
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[[Category: Weigelt J]]
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[[Category: Wyatt, P G]]
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[[Category: Wernimont AK]]
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[[Category: Chaperone]]
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[[Category: Wyatt PG]]
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[[Category: Drug discovery]]
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[[Category: Hsp90]]
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[[Category: Sgc]]
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[[Category: Trypanosoma bruceii]]
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Current revision

Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a thienopyrimidine derivative

PDB ID 3omu

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