6f3k
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Combined solid-state NMR, solution-state NMR and EM data for structure determination of the tetrahedral aminopeptidase TET2 from P. horikoshii== | |
| + | <SX load='6f3k' size='340' side='right' viewer='molstar' caption='[[6f3k]], [[Resolution|resolution]] 4.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6f3k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6F3K FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy , Hybrid , Solid-state NMR , Solution NMR, [[Resolution|Resolution]] 4.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6f3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f3k OCA], [https://pdbe.org/6f3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6f3k RCSB], [https://www.ebi.ac.uk/pdbsum/6f3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6f3k ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TET_PYRHO TET_PYRHO] Functions as an aminopeptidase, with a clear preference for leucine as the N-terminal amino acid. However, can also cleave moderately long polypeptide substrates of various compositions in a fairly unspecific manner. Has neither carboxypeptidase nor endoproteolytic activities, and it is devoid of N-terminal deblocking activity. Is involved in protein degradation, performing degradation of oligopeptides produced by the proteasome into single amino acids.<ref>PMID:15375159</ref> <ref>PMID:15713475</ref> <ref>PMID:15736957</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Boisbouvier | + | </SX> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Gauto | + | [[Category: Pyrococcus horikoshii OT3]] |
| - | [[Category: | + | [[Category: Boisbouvier J]] |
| - | [[Category: Schanda | + | [[Category: Colletier JP]] |
| - | [[Category: Schwieters | + | [[Category: Effantin G]] |
| - | [[Category: | + | [[Category: Estrozi LF]] |
| + | [[Category: Favier A]] | ||
| + | [[Category: Gauto DF]] | ||
| + | [[Category: Kerfah R]] | ||
| + | [[Category: Macek P]] | ||
| + | [[Category: Schanda P]] | ||
| + | [[Category: Schoehn G]] | ||
| + | [[Category: Schwieters CD]] | ||
| + | [[Category: Sivertsen AC]] | ||
| + | [[Category: Sounier R]] | ||
Current revision
Combined solid-state NMR, solution-state NMR and EM data for structure determination of the tetrahedral aminopeptidase TET2 from P. horikoshii
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