6f4u
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of reactive loop cleaved kallistatin at 1.9 angstrom resolution== | |
| + | <StructureSection load='6f4u' size='340' side='right'caption='[[6f4u]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6f4u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6F4U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6f4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f4u OCA], [https://pdbe.org/6f4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6f4u RCSB], [https://www.ebi.ac.uk/pdbsum/6f4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6f4u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KAIN_HUMAN KAIN_HUMAN] Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.<ref>PMID:8227002</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Serpin 3D structures|Serpin 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lin F]] | ||
| + | [[Category: Wei Z]] | ||
| + | [[Category: Zhou A]] | ||
Current revision
Crystal structure of reactive loop cleaved kallistatin at 1.9 angstrom resolution
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Categories: Homo sapiens | Large Structures | Lin F | Wei Z | Zhou A
