6f5b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of ARTD2/PARP2 WGR domain bound to double stranded DNA with 5'phosphate== | |
| + | <StructureSection load='6f5b' size='340' side='right'caption='[[6f5b]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6f5b]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6F5B FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6f5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f5b OCA], [https://pdbe.org/6f5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6f5b RCSB], [https://www.ebi.ac.uk/pdbsum/6f5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6f5b ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PARP2_HUMAN PARP2_HUMAN] Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. | ||
| - | + | ==See Also== | |
| - | + | *[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Haikarainen T]] | ||
| + | [[Category: Lehtio L]] | ||
| + | [[Category: Obaji E]] | ||
Current revision
Structure of ARTD2/PARP2 WGR domain bound to double stranded DNA with 5'phosphate
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