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5lob

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Current revision (18:37, 18 October 2023) (edit) (undo)
 
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==Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group)==
==Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group)==
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<StructureSection load='5lob' size='340' side='right' caption='[[5lob]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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<StructureSection load='5lob' size='340' side='right'caption='[[5lob]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5lob]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LOB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5lob]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LOB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rph3a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat]), Snap25, Snap ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lob OCA], [https://pdbe.org/5lob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lob RCSB], [https://www.ebi.ac.uk/pdbsum/5lob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lob ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lob OCA], [http://pdbe.org/5lob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lob RCSB], [http://www.ebi.ac.uk/pdbsum/5lob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lob ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT]] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
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[https://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5lob" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5lob" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Exophilin 3D structures|Exophilin 3D structures]]
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*[[Rabphilin|Rabphilin]]
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*[[Synaptosomal-associated protein|Synaptosomal-associated protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
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[[Category: Large Structures]]
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[[Category: Ferrer-Orta, C]]
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[[Category: Rattus norvegicus]]
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[[Category: Verdaguer, N]]
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[[Category: Ferrer-Orta C]]
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[[Category: C2 domain]]
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[[Category: Verdaguer N]]
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[[Category: Exocytosis]]
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[[Category: Membrane fusion]]
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[[Category: Pip2]]
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[[Category: Snare complex]]
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Current revision

Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group)

PDB ID 5lob

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