This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5low

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:38, 18 October 2023) (edit) (undo)
 
Line 1: Line 1:
==Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)==
==Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)==
-
<StructureSection load='5low' size='340' side='right' caption='[[5low]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+
<StructureSection load='5low' size='340' side='right'caption='[[5low]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5low]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LOW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5low]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LOW FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rph3a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat]), Snap25, Snap ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5low FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5low OCA], [http://pdbe.org/5low PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5low RCSB], [http://www.ebi.ac.uk/pdbsum/5low PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5low ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5low FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5low OCA], [https://pdbe.org/5low PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5low RCSB], [https://www.ebi.ac.uk/pdbsum/5low PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5low ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT]] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. [[http://www.uniprot.org/uniprot/SNP25_RAT SNP25_RAT]] t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
+
[https://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 5low" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5low" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Exophilin 3D structures|Exophilin 3D structures]]
 +
*[[Rabphilin|Rabphilin]]
 +
*[[Synaptosomal-associated protein|Synaptosomal-associated protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Buffalo rat]]
+
[[Category: Large Structures]]
-
[[Category: Ferrer-Orta, C]]
+
[[Category: Rattus norvegicus]]
-
[[Category: Verdaguer, N]]
+
[[Category: Ferrer-Orta C]]
-
[[Category: C2 domain]]
+
[[Category: Verdaguer N]]
-
[[Category: Calcium]]
+
-
[[Category: Exocytosis]]
+
-
[[Category: Membrane fusion]]
+

Current revision

Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)

PDB ID 5low

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5low"
Personal tools