6bm0
From Proteopedia
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==Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution== | ==Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution== | ||
| - | < | + | <SX load='6bm0' size='340' side='right' viewer='molstar' caption='[[6bm0]], [[Resolution|resolution]] 3.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6bm0]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6bm0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BM0 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bm0 OCA], [https://pdbe.org/6bm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bm0 RCSB], [https://www.ebi.ac.uk/pdbsum/6bm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bm0 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CPSF1_HUMAN CPSF1_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.<ref>PMID:14749727</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Hamilton | + | [[Category: Large Structures]] |
| - | [[Category: Sun | + | [[Category: Hamilton K]] |
| - | [[Category: Tong | + | [[Category: Sun Y]] |
| - | [[Category: Walz | + | [[Category: Tong L]] |
| - | [[Category: Zhang | + | [[Category: Walz T]] |
| - | + | [[Category: Zhang Y]] | |
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Current revision
Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution
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Categories: Homo sapiens | Large Structures | Hamilton K | Sun Y | Tong L | Walz T | Zhang Y
