Mandelate racemase/muconate lactonizing enzyme

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== Structural highlights ==
== Structural highlights ==
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The D-mannonate dehydratase has <scene name='77/775266/Cv/6'>two domains</scene>: the <scene name='77/775266/Cv/7'>N-terminal α+β domain</scene> and a <scene name='77/775266/Cv/8'>(β/α)<sub>7</sub> β-barrel domain</scene>. The <scene name='77/775266/Cv/4'>active site</scene> of the enzyme is found between these two domains<ref>PMID:179444491</ref>. <scene name='77/775266/Cv/5'>Mg coordination site</scene>.
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The D-mannonate dehydratase has <scene name='77/775266/Cv/9'>two domains</scene>: the <scene name='77/775266/Cv/10'>N-terminal α+β domain</scene> and a <scene name='77/775266/Cv/11'>(β/α)<sub>7</sub> β-barrel domain</scene>. The <scene name='77/775266/Cv/12'>active site</scene> of the enzyme is found between these two domains<ref>PMID:179444491</ref>. Water molecules are shown as red spheres. <scene name='77/775266/Cv/13'>Mg coordination site</scene>.
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</StructureSection>
 
== 3D Structures of Mandelate racemase/muconate lactonizing enzyme ==
== 3D Structures of Mandelate racemase/muconate lactonizing enzyme ==
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[[Mandelate racemase/muconate lactonizing enzyme 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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</StructureSection>
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Mandelate racemate/muconate lactonizing enzyme
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**[[3mqt]], [[3sjn]] – MRMLP – ''Shewanella pealeana''<br />
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**[[3msy]], [[4h83]], [[3no1]] – MRMLP – ''Actinobacterium''<br />
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**[[3ssz]] – MRMLP – ''Rhodobacteraceae bacterium''<br />
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**[[3t4w]] – MRMLP – ''Sulfitobacter''<br />
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**[[3u9i]] – MRMLP – ''Roseiflexus''<br />
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**[[3ik4]] – MRMLP – ''Herpetosiphon aurantiacus''<br />
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**[[2gdq]], [[2gge]] – MRMLP – ''Bacillus subtilis''<br />
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**[[2og9]], [[3bjs]] – PoMRMLP – ''Polaromonas''<br />
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**[[2pmq]], [[2rdx]], [[3u4f]], [[2qdd]], [[3fvd]] – MRMLP – ''Roseovarius''<br />
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**[[3tmq]] – MRMLP (mutant) – ''Hoeflea phototrophica''<br />
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**[[4j3z]] – MRMLP – ''Jannaschia''<br />
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**[[2qde]] – MRMLP – ''Azoarcus''<br />
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**[[3n4e]], [[4dwd]], [[4e8g]] – PdMRMLP – ''Paracoccus dentrificans''<br />
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**[[4dx3]], [[4dxk]] – AtMRMLP – ''Agrobacterium tumefaciens''<br />
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**[[3toy]] – BrMRMLP – ''Bradyrhizobium''<br />
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**[[3bsm]], [[3ow1]], [[3pk7]] – CsMRMLP – ''Chromohalobacter salexigens''<br />
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**[[1wue]] – MRMLP – ''Enterococcus faecalis''<br />
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**[[4hnl]] – MRMLP – ''Enterococcus gallinarum''<br />
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**[[3tji]] – MRMLP – ''Enterobacter''<br />
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**[[2pod]] – MRMLP – ''Burkholderia pseudomallei''<br />
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**[[2qjj]] – NaMRMLP – ''Novosphignobium aromaticivorans''<br />
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**[[4k8g]] – NaMRMLP (mutant) <br />
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**[[3vc5]], [[3vc6]], [[3vcc]], [[4dhg]] – MRMLP – ''Thermobispora bispora''<br />
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**[[3r25]] – VbMRMLP – ''Vibrionales bacterium'' <br />
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**[[3v5c]], [[3v5f]] – GeMRMLP (mutant) - ''Geobacillus''<br />
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**[[2oz3]] – AvMRMLP – ''Azotobacter vinelandii''<br />
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**[[2p88]] – BcMRMLP – ''Bacillus cereus''<br />
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**[[4fi4]], [[3vcn]] – CcMRMLP - ''Caulobacter crescentus''<br />
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**[[3thu]] – MRMLP - ''Sphigomonas''<br />
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**[[4ip4]] – SiMRMLP - ''Silicibacter''<br />
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*Mandelate racemate/muconate lactonizing enzyme complex
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**[[3tte]] – BrMRMLP + mandelate <br />
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**[[2qjn]] – NaMRMLP + gluconate derivative <br />
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**[[2qjm]], [[4k1w]] – NaMRMLP (mutant) + D-mannonate <br />
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**[[4gme]] – CcMRMLP + D-mannonate <br />
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**[[4h2h]] – MRMLP + betonicine – ''Pelagibaca bermudensis''<br />
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**[[4j1o]], [[4izg]] – PdMRMLP + betonicine<br />
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**[[3cb3]] – PoMRMLP + glucarate <br />
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**[[3p0w]] – MRMLP + glucarate – ''Ralstonia solanacearum''<br />
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**[[3ekg]] – AvMRMLP + tartrate <br />
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**[[3p3b]] – GeMRMLP + tarrate <br />
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**[[3qpe]] – GeMRMLP + galacturonate <br />
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**[[3qke]] – CsMRMLP + gluconate <br />
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**[[3p93]] – CsMRMLP + gluconate + mannonate<br />
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**[[4kem]] – MRMLP + acrylate – ''Azospirillum''<br />
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**[[2p8b]] – BcMRMLP + N-succinyl Lys <br />
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**[[2p8c]] – BcMRMLP + N-succinyl Arg <br />
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**[[3sbf]] – VbMRMLP + arabinonate <br />
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**[[4gfi]] – AtMRMLP + dipeptide <br />
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**[[3q45]], [[3q4d]] – MRMLP + dipeptide – ''Cytophaga hutchinsonii'' <br />
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**[[4ip5]] – SiMRMLP + erythronohydroxamate <br />
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}}
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== References ==
== References ==

Current revision

MRMLP complex with D-mannonate and Mg+2 ion (green) (PDB code 2qjm)

Drag the structure with the mouse to rotate

References

  1. ↑ . PMID:179444491

Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Michal Harel, Alexander Berchansky

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