6bs2

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(New page: '''Unreleased structure''' The entry 6bs2 is ON HOLD Authors: Kumar, G., Wang, Y., Li, W., White, S.W. Description: Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound...)
Current revision (14:24, 13 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6bs2 is ON HOLD
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==Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 8b==
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<StructureSection load='6bs2' size='340' side='right'caption='[[6bs2]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bs2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BS2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=E9Y:1-(3,6-dimethyl[1,2]oxazolo[5,4-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline'>E9Y</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bs2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bs2 OCA], [https://pdbe.org/6bs2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bs2 RCSB], [https://www.ebi.ac.uk/pdbsum/6bs2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bs2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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Authors: Kumar, G., Wang, Y., Li, W., White, S.W.
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==See Also==
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*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
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Description: Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 8b
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*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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[[Category: Unreleased Structures]]
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*[[Tubulin tyrosine ligase 3D structures|Tubulin tyrosine ligase 3D structures]]
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[[Category: White, S.W]]
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__TOC__
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[[Category: Kumar, G]]
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</StructureSection>
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[[Category: Wang, Y]]
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[[Category: Gallus gallus]]
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[[Category: Li, W]]
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[[Category: Large Structures]]
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[[Category: Rattus norvegicus]]
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[[Category: Sus scrofa]]
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[[Category: Kumar G]]
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[[Category: Li W]]
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[[Category: Wang Y]]
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[[Category: White SW]]

Current revision

Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 8b

PDB ID 6bs2

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