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1e80

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==Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133==
==Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133==
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<StructureSection load='1e80' size='340' side='right' caption='[[1e80]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='1e80' size='340' side='right'caption='[[1e80]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1e80]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Endothia_parasitica Endothia parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E80 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E80 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1e80]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E80 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0GQ:4-AMINO-N-{(1R,8R,9R,13R)-16-(4-AMINO-2-METHYLPYRIMIDIN-5-YL)-1-BENZYL-8-(CYCLOHEXYLMETHYL)-9-HYDROXY-13-[(1S)-1-METHYLPROPYL]-2,6,11,14-TETRAOXO-3,7,12,15-TETRAAZAHEXADEC-1-YL}PIPERIDINE-1-CARBOXAMIDE'>0GQ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ape|4ape]], [[1e5o|1e5o]], [[1e81|1e81]], [[1e82|1e82]], [[1eed|1eed]], [[1ent|1ent]], [[2er0|2er0]], [[4er1|4er1]], [[5er1|5er1]], [[4er2|4er2]], [[5er2|5er2]], [[3er3|3er3]], [[4er4|4er4]], [[3er5|3er5]], [[2er6|2er6]], [[2er7|2er7]], [[1er8|1er8]], [[2er9|2er9]], [[1epl|1epl]], [[1epm|1epm]], [[1epn|1epn]], [[1epo|1epo]], [[1epp|1epp]], [[1epq|1epq]], [[1epr|1epr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0GQ:4-AMINO-N-{(1R,8R,9R,13R)-16-(4-AMINO-2-METHYLPYRIMIDIN-5-YL)-1-BENZYL-8-(CYCLOHEXYLMETHYL)-9-HYDROXY-13-[(1S)-1-METHYLPROPYL]-2,6,11,14-TETRAOXO-3,7,12,15-TETRAAZAHEXADEC-1-YL}PIPERIDINE-1-CARBOXAMIDE'>0GQ</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e80 OCA], [https://pdbe.org/1e80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e80 RCSB], [https://www.ebi.ac.uk/pdbsum/1e80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e80 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e80 OCA], [http://pdbe.org/1e80 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1e80 RCSB], [http://www.ebi.ac.uk/pdbsum/1e80 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1e80 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[User:Luca Toldo|User:Luca Toldo]]
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*[[Pepsin|Pepsin]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Endothia parasitica]]
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[[Category: Cryphonectria parasitica]]
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[[Category: Mucorpepsin]]
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[[Category: Large Structures]]
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[[Category: Cooper, J B]]
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[[Category: Cooper JB]]
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[[Category: Raddatz, P]]
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[[Category: Raddatz P]]
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[[Category: Read, J A]]
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[[Category: Read JA]]
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[[Category: Rippmann, F]]
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[[Category: Rippmann F]]
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[[Category: Toldo, L]]
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[[Category: Toldo L]]
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[[Category: Acid proteinase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133

PDB ID 1e80

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