5yza
From Proteopedia
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(New page: '''Unreleased structure''' The entry 5yza is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human CRMP-2 with S522D mutation== | |
| - | + | <StructureSection load='5yza' size='340' side='right'caption='[[5yza]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yza]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YZA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yza OCA], [https://pdbe.org/5yza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yza RCSB], [https://www.ebi.ac.uk/pdbsum/5yza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yza ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPYL2_HUMAN DPYL2_HUMAN] Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Plays a role in neuron projection morphogenesis.<ref>PMID:11477421</ref> <ref>PMID:15466863</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Aoki M]] | ||
| + | [[Category: Imasaki T]] | ||
| + | [[Category: Nitta E]] | ||
| + | [[Category: Nitta R]] | ||
| + | [[Category: Sakai N]] | ||
| + | [[Category: Shirouzu M]] | ||
| + | [[Category: Sumi T]] | ||
Current revision
Crystal Structure of Human CRMP-2 with S522D mutation
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Categories: Homo sapiens | Large Structures | Aoki M | Imasaki T | Nitta E | Nitta R | Sakai N | Shirouzu M | Sumi T
