6f7g
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6f7g is ON HOLD Authors: Stiel, A.C., Shanmugaratnam, S., Hocker, B. Description: Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine [[C...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine== | |
| - | + | <StructureSection load='6f7g' size='340' side='right'caption='[[6f7g]], [[Resolution|resolution]] 1.66Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6f7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F7G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CVW:2-(5-methyl-1~{H}-indol-3-yl)ethanamine'>CVW</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpR, rtrY, b4393, JW4356 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f7g OCA], [http://pdbe.org/6f7g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f7g RCSB], [http://www.ebi.ac.uk/pdbsum/6f7g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f7g ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus coli migula 1895]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hocker, B]] | [[Category: Hocker, B]] | ||
[[Category: Shanmugaratnam, S]] | [[Category: Shanmugaratnam, S]] | ||
| - | [[Category: Stiel, A | + | [[Category: Stiel, A C]] |
| + | [[Category: Ligand binding]] | ||
| + | [[Category: Transcription]] | ||
Current revision
Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine
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