This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6bst
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==CRYSTAL STRUCTURE OF Z-DNA WITH UNTYPICALLY COORDINATED CA2+ ION== | ==CRYSTAL STRUCTURE OF Z-DNA WITH UNTYPICALLY COORDINATED CA2+ ION== | ||
| - | <StructureSection load='6bst' size='340' side='right' caption='[[6bst]], [[Resolution|resolution]] 1.45Å' scene=''> | + | <StructureSection load='6bst' size='340' side='right'caption='[[6bst]], [[Resolution|resolution]] 1.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6bst]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6b01 6b01]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BST OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6bst]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6b01 6b01]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BST FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SR0:N~1~-(3-azaniumylpropyl)butane-1,4-diaminium'>SR0</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SR0:N~1~-(3-azaniumylpropyl)butane-1,4-diaminium'>SR0</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bst OCA], [https://pdbe.org/6bst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bst RCSB], [https://www.ebi.ac.uk/pdbsum/6bst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bst ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | DNA oligomer duplexes with alternating cytosines and guanines in their sequence tend to form helices of the Z-DNA type, where the sugar and phosphate backbone forms a left-handed helix in a zigzag fashion with a repeat of two successive Watson-Crick pairs of nucleotides. Z-DNA duplexes often crystallize in complexes with diverse metal ions interacting with polar DNA atoms in various ways. This work describes the high-resolution crystal structure of a Z-DNA d(CGCGCG)2 duplex in complex with Ca(2+) ions, unusually coordinated as an approximate pentagonal bipyramid by two neighboring guanines through their O6 and N7 atoms and a water molecule in the equatorial plane and a phosphate oxygen atom and another water molecule in the apical positions. | ||
| + | |||
| + | The crystal structure of Z-DNA with untypically coordinated Ca(2+) ions.,Luo Z, Dauter Z J Biol Inorg Chem. 2017 Dec 21. pii: 10.1007/s00775-017-1526-4. doi:, 10.1007/s00775-017-1526-4. PMID:29270817<ref>PMID:29270817</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6bst" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Z-DNA|Z-DNA]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: DAUTER Z]] |
| - | + | [[Category: LUO Z]] | |
| - | [[Category: Z | + | |
Current revision
CRYSTAL STRUCTURE OF Z-DNA WITH UNTYPICALLY COORDINATED CA2+ ION
| |||||||||||
