1f05

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==CRYSTAL STRUCTURE OF HUMAN TRANSALDOLASE==
==CRYSTAL STRUCTURE OF HUMAN TRANSALDOLASE==
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<StructureSection load='1f05' size='340' side='right' caption='[[1f05]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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<StructureSection load='1f05' size='340' side='right'caption='[[1f05]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1f05]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1F05 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1f05]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F05 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1onr|1onr]], [[1ucw|1ucw]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transaldolase Transaldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.2 2.2.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f05 OCA], [https://pdbe.org/1f05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f05 RCSB], [https://www.ebi.ac.uk/pdbsum/1f05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f05 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f05 OCA], [http://pdbe.org/1f05 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1f05 RCSB], [http://www.ebi.ac.uk/pdbsum/1f05 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1f05 ProSAT]</span></td></tr>
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</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/TALDO_HUMAN TALDO_HUMAN]] Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:[http://omim.org/entry/606003 606003]]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris.
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[https://www.uniprot.org/uniprot/TALDO_HUMAN TALDO_HUMAN] Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:[https://omim.org/entry/606003 606003]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TALDO_HUMAN TALDO_HUMAN]] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
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[https://www.uniprot.org/uniprot/TALDO_HUMAN TALDO_HUMAN] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1f05" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1f05" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Transaldolase 3D structures|Transaldolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Transaldolase]]
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[[Category: Large Structures]]
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[[Category: Schneider, G]]
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[[Category: Schneider G]]
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[[Category: Thorell, S]]
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[[Category: Thorell S]]
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[[Category: Alpha-beta barrel]]
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[[Category: Transferase]]
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Current revision

CRYSTAL STRUCTURE OF HUMAN TRANSALDOLASE

PDB ID 1f05

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