This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6bp8
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1== | |
| - | + | <SX load='6bp8' size='340' side='right' viewer='molstar' caption='[[6bp8]], [[Resolution|resolution]] 4.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bp8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BP8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.9Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bp8 OCA], [https://pdbe.org/6bp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bp8 RCSB], [https://www.ebi.ac.uk/pdbsum/6bp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bp8 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MVP_RAT MVP_RAT] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Ding K]] | ||
| + | [[Category: Kickhoefer VA]] | ||
| + | [[Category: Lai M]] | ||
| + | [[Category: Mrazek J]] | ||
| + | [[Category: Ng HL]] | ||
| + | [[Category: Rome LH]] | ||
| + | [[Category: Yang OO]] | ||
| + | [[Category: Zhang X]] | ||
| + | [[Category: Zhou ZH]] | ||
Current revision
Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1
| |||||||||
Categories: Large Structures | Rattus norvegicus | Ding K | Kickhoefer VA | Lai M | Mrazek J | Ng HL | Rome LH | Yang OO | Zhang X | Zhou ZH
