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6bxx

From Proteopedia

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(New page: '''Unreleased structure''' The entry 6bxx is ON HOLD Authors: Hughes, M.P., Rodriguez, J.A., Sawaya, M.R., Cascio, D., Gonen, T., Eisenberg, D.S. Description: GYNGFG from low-complexit...)
Current revision (14:24, 13 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 6bxx is ON HOLD
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==GYNGFG from low-complexity domain of hnRNPA1, residues 243-248==
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<StructureSection load='6bxx' size='340' side='right'caption='[[6bxx]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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Authors: Hughes, M.P., Rodriguez, J.A., Sawaya, M.R., Cascio, D., Gonen, T., Eisenberg, D.S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bxx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BXX FirstGlance]. <br>
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Description: GYNGFG from low-complexity domain of hnRNPA1, residues 243-248
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bxx OCA], [https://pdbe.org/6bxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bxx RCSB], [https://www.ebi.ac.uk/pdbsum/6bxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bxx ProSAT]</span></td></tr>
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[[Category: Sawaya, M.R]]
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</table>
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[[Category: Hughes, M.P]]
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== Disease ==
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[[Category: Gonen, T]]
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
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[[Category: Rodriguez, J.A]]
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== Function ==
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[[Category: Eisenberg, D.S]]
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>
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[[Category: Cascio, D]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cascio D]]
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[[Category: Eisenberg DS]]
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[[Category: Gonen T]]
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[[Category: Hughes MP]]
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[[Category: Rodriguez JA]]
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[[Category: Sawaya MR]]

Current revision

GYNGFG from low-complexity domain of hnRNPA1, residues 243-248

PDB ID 6bxx

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