6fal
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6fal is ON HOLD Authors: Stiel, A.C., Shanmugaratnam, S., Hocker, B. Description: Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand== | |
| - | + | <StructureSection load='6fal' size='340' side='right'caption='[[6fal]], [[Resolution|resolution]] 1.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FAL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOP:INDOLYLPROPIONIC+ACID'>IOP</scene></td></tr> |
| - | [[Category: Hocker | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fal OCA], [https://pdbe.org/6fal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fal RCSB], [https://www.ebi.ac.uk/pdbsum/6fal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fal ProSAT]</span></td></tr> |
| - | [[Category: Shanmugaratnam | + | </table> |
| - | [[Category: Stiel | + | == Function == |
| + | [https://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hocker B]] | ||
| + | [[Category: Shanmugaratnam S]] | ||
| + | [[Category: Stiel AC]] | ||
Current revision
Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand
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