2cov

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[[Image:2cov.gif|left|200px]]
 
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{{Structure
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==Crystal structure of CBM31 from beta-1,3-xylanase==
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|PDB= 2cov |SIZE=350|CAPTION= <scene name='initialview01'>2cov</scene>, resolution 1.25&Aring;
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<StructureSection load='2cov' size='340' side='right'caption='[[2cov]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2cov]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_sp._XY-234 Alcaligenes sp. XY-234]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2COV FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cov OCA], [https://pdbe.org/2cov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cov RCSB], [https://www.ebi.ac.uk/pdbsum/2cov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cov ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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<div style="background-color:#fffaf0;">
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cov OCA], [http://www.ebi.ac.uk/pdbsum/2cov PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2cov RCSB]</span>
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== Publication Abstract from PubMed ==
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}}
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'''Crystal structure of CBM31 from beta-1,3-xylanase'''
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==Overview==
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Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds.
Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds.
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==About this Structure==
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The first crystal structure of a family 31 carbohydrate-binding module with affinity to beta-1,3-xylan.,Hashimoto H, Tamai Y, Okazaki F, Tamaru Y, Shimizu T, Araki T, Sato M FEBS Lett. 2005 Aug 15;579(20):4324-8. PMID:16061225<ref>PMID:16061225</ref>
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2COV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Alcaligenes_sp. Alcaligenes sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COV OCA].
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==Reference==
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The first crystal structure of a family 31 carbohydrate-binding module with affinity to beta-1,3-xylan., Hashimoto H, Tamai Y, Okazaki F, Tamaru Y, Shimizu T, Araki T, Sato M, FEBS Lett. 2005 Aug 15;579(20):4324-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16061225 16061225]
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[[Category: Alcaligenes sp.]]
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[[Category: Single protein]]
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[[Category: Araki, T.]]
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[[Category: Hashimoto, H.]]
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[[Category: Okazaki, F.]]
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[[Category: Sato, M.]]
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[[Category: Shimizu, T.]]
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[[Category: Tamai, Y.]]
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[[Category: Tamaru, Y.]]
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[[Category: beta-1,3-xylanase]]
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[[Category: carbohydrate-binding module]]
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[[Category: family 31 cbm]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:24:36 2008''
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2cov" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Alcaligenes sp. XY-234]]
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[[Category: Large Structures]]
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[[Category: Araki T]]
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[[Category: Hashimoto H]]
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[[Category: Okazaki F]]
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[[Category: Sato M]]
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[[Category: Shimizu T]]
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[[Category: Tamai Y]]
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[[Category: Tamaru Y]]

Current revision

Crystal structure of CBM31 from beta-1,3-xylanase

PDB ID 2cov

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