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5y7a

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==Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN==
==Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN==
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<StructureSection load='5y7a' size='340' side='right' caption='[[5y7a]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='5y7a' size='340' side='right'caption='[[5y7a]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5y7a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y7A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5y7a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y7A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=KYN:(2S)-2-AMINO-4-(2-AMINOPHENYL)-4-OXOBUTANOIC+ACID'>KYN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.846&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5y66|5y66]], [[5y77|5y77]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=KYN:(2S)-2-AMINO-4-(2-AMINOPHENYL)-4-OXOBUTANOIC+ACID'>KYN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Kynurenine_3-monooxygenase Kynurenine 3-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.9 1.14.13.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y7a OCA], [https://pdbe.org/5y7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y7a RCSB], [https://www.ebi.ac.uk/pdbsum/5y7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y7a ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y7a OCA], [http://pdbe.org/5y7a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y7a RCSB], [http://www.ebi.ac.uk/pdbsum/5y7a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y7a ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KMO_PSEFL KMO_PSEFL]] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Probably required for the synthesis of quinolinic acid and the siderophore quinolobactin.
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[https://www.uniprot.org/uniprot/KMO_PSEFL KMO_PSEFL] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Probably required for the synthesis of quinolinic acid and the siderophore quinolobactin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5y7a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5y7a" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Kynurenine 3-monooxygenase]]
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[[Category: Large Structures]]
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[[Category: Gao, J J]]
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[[Category: Pseudomonas fluorescens]]
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[[Category: Xiang, Y]]
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[[Category: Gao JJ]]
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[[Category: Zhu, D Y]]
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[[Category: Xiang Y]]
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[[Category: Enzyme]]
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[[Category: Zhu DY]]
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[[Category: Kmo]]
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[[Category: Oxidoreductase]]
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[[Category: Ro61-8048]]
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Current revision

Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN

PDB ID 5y7a

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