1fxk

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==CRYSTAL STRUCTURE OF ARCHAEAL PREFOLDIN (GIMC).==
==CRYSTAL STRUCTURE OF ARCHAEAL PREFOLDIN (GIMC).==
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<StructureSection load='1fxk' size='340' side='right' caption='[[1fxk]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='1fxk' size='340' side='right'caption='[[1fxk]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1fxk]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"methanobacterium_thermoautotrophicus"_(sic)_zeikus_and_wolfe_1972 "methanobacterium thermoautotrophicus" (sic) zeikus and wolfe 1972]. The August 2002 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Chaperones'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2002_8 10.2210/rcsb_pdb/mom_2002_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FXK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FXK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1fxk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. The August 2002 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Chaperones'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2002_8 10.2210/rcsb_pdb/mom_2002_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FXK FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fxk OCA], [http://pdbe.org/1fxk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fxk RCSB], [http://www.ebi.ac.uk/pdbsum/1fxk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fxk ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fxk OCA], [https://pdbe.org/1fxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fxk RCSB], [https://www.ebi.ac.uk/pdbsum/1fxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fxk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PFDB_METTH PFDB_METTH]] Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. [[http://www.uniprot.org/uniprot/PFDA_METTH PFDA_METTH]] Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
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[https://www.uniprot.org/uniprot/PFDB_METTH PFDB_METTH] Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fx/1fxk_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fx/1fxk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Chaperones]]
[[Category: Chaperones]]
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[[Category: Large Structures]]
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[[Category: Methanothermobacter thermautotrophicus]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Moarefi, I]]
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[[Category: Moarefi I]]
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[[Category: Scheufler, C]]
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[[Category: Scheufler C]]
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[[Category: Siegert, R]]
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[[Category: Siegert R]]
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[[Category: Archaeal protein]]
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[[Category: Chaperone]]
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Current revision

CRYSTAL STRUCTURE OF ARCHAEAL PREFOLDIN (GIMC).

PDB ID 1fxk

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