6fe6
From Proteopedia
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(New page: '''Unreleased structure''' The entry 6fe6 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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- | '''Unreleased structure''' | ||
- | + | ==Solution structure of a last generation P2-P4 macrocyclic inhibitor== | |
- | + | <StructureSection load='6fe6' size='340' side='right'caption='[[6fe6]], [[NMR_Ensembles_of_Models | 18 NMR models]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6fe6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FE6 FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4P2:(3aR,7S,10S,12R,24aR)-7-cyclopentyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-5,8-dioxo-1,2,3,3a,5,6,7,8,11,12,20,21,22,23,24,24a-hexadecahydro-10H-9,12-methanocyclopenta[18,19][1,10,3,6]dioxadiazacyclononadecino[12,11-b]quinoline-10-carboxamide'>4P2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fe6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fe6 OCA], [http://pdbe.org/6fe6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fe6 RCSB], [http://www.ebi.ac.uk/pdbsum/6fe6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fe6 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Hepatitis c virus subtype 1b]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Cicero, D O]] | ||
+ | [[Category: Eliseo, T]] | ||
+ | [[Category: Gallo, M]] | ||
+ | [[Category: Complex]] | ||
+ | [[Category: Hcv]] | ||
+ | [[Category: Inhibitor]] | ||
+ | [[Category: Ns3 protease]] | ||
+ | [[Category: Viral protein]] |
Current revision
Solution structure of a last generation P2-P4 macrocyclic inhibitor
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