6arx

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==Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in the ligand-free state==
==Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in the ligand-free state==
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<StructureSection load='6arx' size='340' side='right' caption='[[6arx]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='6arx' size='340' side='right'caption='[[6arx]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6arx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ARX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6arx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ARX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ARX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.302&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6arx OCA], [http://pdbe.org/6arx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6arx RCSB], [http://www.ebi.ac.uk/pdbsum/6arx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6arx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6arx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6arx OCA], [https://pdbe.org/6arx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6arx RCSB], [https://www.ebi.ac.uk/pdbsum/6arx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6arx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACES_ANOGA ACES_ANOGA]] Rapidly hydrolyzes choline released into the synapse.
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[https://www.uniprot.org/uniprot/ACES_ANOGA ACES_ANOGA] Rapidly hydrolyzes choline released into the synapse.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6arx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6arx" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acetylcholinesterase]]
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[[Category: Anopheles gambiae]]
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[[Category: Carlier, P R]]
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[[Category: Large Structures]]
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[[Category: Cheung, J]]
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[[Category: Carlier PR]]
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[[Category: Kalathur, R]]
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[[Category: Cheung J]]
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[[Category: Lixuan, L]]
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[[Category: Kalathur R]]
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[[Category: Mahmood, A]]
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[[Category: Lixuan L]]
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[[Category: Hydrolase]]
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[[Category: Mahmood A]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in the ligand-free state

PDB ID 6arx

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