1hyb

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==CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE==
==CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE==
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<StructureSection load='1hyb' size='340' side='right' caption='[[1hyb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1hyb' size='340' side='right'caption='[[1hyb]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hyb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"methanobacterium_thermoautotrophicus"_(sic)_zeikus_and_wolfe_1972 "methanobacterium thermoautotrophicus" (sic) zeikus and wolfe 1972]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HYB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HYB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HYB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NMN:BETA-NICOTINAMIDE+RIBOSE+MONOPHOSPHATE'>NMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ej2|1ej2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NMN:BETA-NICOTINAMIDE+RIBOSE+MONOPHOSPHATE'>NMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nicotinamide-nucleotide_adenylyltransferase Nicotinamide-nucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.1 2.7.7.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hyb OCA], [https://pdbe.org/1hyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hyb RCSB], [https://www.ebi.ac.uk/pdbsum/1hyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hyb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hyb OCA], [http://pdbe.org/1hyb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hyb RCSB], [http://www.ebi.ac.uk/pdbsum/1hyb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hyb ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NADM_METTH NADM_METTH]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1hyb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1hyb" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Nicotinamide mononucleotide adenylyltransferase|Nicotinamide mononucleotide adenylyltransferase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Nicotinamide-nucleotide adenylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Christendat, D]]
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[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Edwards, A M]]
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[[Category: Christendat D]]
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[[Category: Kimber, M S]]
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[[Category: Edwards AM]]
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[[Category: Pai, E F]]
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[[Category: Kimber MS]]
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[[Category: Saridakis, V]]
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[[Category: Pai EF]]
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[[Category: Active site mutant]]
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[[Category: Saridakis V]]
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[[Category: Dinucleotide binding fold]]
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[[Category: Transferase]]
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Current revision

CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE

PDB ID 1hyb

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