2d4a

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[[Image:2d4a.gif|left|200px]]
 
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{{Structure
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==Structure of the malate dehydrogenase from Aeropyrum pernix==
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|PDB= 2d4a |SIZE=350|CAPTION= <scene name='initialview01'>2d4a</scene>, resolution 2.87&Aring;
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<StructureSection load='2d4a' size='340' side='right'caption='[[2d4a]], [[Resolution|resolution]] 2.87&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2d4a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D4A FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.87&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d4a OCA], [https://pdbe.org/2d4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d4a RCSB], [https://www.ebi.ac.uk/pdbsum/2d4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d4a ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d4a OCA], [http://www.ebi.ac.uk/pdbsum/2d4a PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2d4a RCSB]</span>
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[https://www.uniprot.org/uniprot/MDH_AERPE MDH_AERPE] Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Has a preference for NADP.<ref>PMID:19555779</ref>
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/2d4a_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d4a ConSurf].
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<div style="clear:both"></div>
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'''Structure of the malate dehydrogenase from Aeropyrum pernix'''
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==See Also==
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*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2D4A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4A OCA].
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__TOC__
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</StructureSection>
[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
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[[Category: Malate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Kawakami R]]
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[[Category: Kawakami, R.]]
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[[Category: Ohshima T]]
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[[Category: Ohshima, T.]]
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[[Category: Sakuraba H]]
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[[Category: Sakuraba, H.]]
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[[Category: Tsuge H]]
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[[Category: Tsuge, H.]]
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[[Category: archaea]]
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[[Category: hyperthermophile]]
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[[Category: malate dehydrogenase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:30:08 2008''
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Current revision

Structure of the malate dehydrogenase from Aeropyrum pernix

PDB ID 2d4a

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