1i1j

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==STRUCTURE OF MELANOMA INHIBITORY ACTIVITY PROTEIN: A MEMBER OF A NEW FAMILY OF SECRETED PROTEINS==
==STRUCTURE OF MELANOMA INHIBITORY ACTIVITY PROTEIN: A MEMBER OF A NEW FAMILY OF SECRETED PROTEINS==
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<StructureSection load='1i1j' size='340' side='right' caption='[[1i1j]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
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<StructureSection load='1i1j' size='340' side='right'caption='[[1i1j]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1i1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I1J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1i1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I1J FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i1j OCA], [http://pdbe.org/1i1j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1i1j RCSB], [http://www.ebi.ac.uk/pdbsum/1i1j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1i1j ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i1j OCA], [https://pdbe.org/1i1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i1j RCSB], [https://www.ebi.ac.uk/pdbsum/1i1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i1j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MIA_HUMAN MIA_HUMAN]] Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
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[https://www.uniprot.org/uniprot/MIA_HUMAN MIA_HUMAN] Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/1i1j_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/1i1j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Alber, T]]
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[[Category: Large Structures]]
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[[Category: Bazan, J F]]
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[[Category: Alber T]]
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[[Category: Handel, T M]]
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[[Category: Bazan JF]]
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[[Category: Holton, J M]]
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[[Category: Handel TM]]
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[[Category: Lougheed, J C]]
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[[Category: Holton JM]]
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[[Category: Hormone-growth factor complex]]
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[[Category: Lougheed JC]]
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[[Category: Sh3 subdomain]]
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Current revision

STRUCTURE OF MELANOMA INHIBITORY ACTIVITY PROTEIN: A MEMBER OF A NEW FAMILY OF SECRETED PROTEINS

PDB ID 1i1j

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