2d7l

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:34, 22 May 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2d7l.gif|left|200px]]
 
-
{{Structure
+
==Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1==
-
|PDB= 2d7l |SIZE=350|CAPTION= <scene name='initialview01'>2d7l</scene>
+
<StructureSection load='2d7l' size='340' side='right'caption='[[2d7l]]' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[2d7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D7L FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
|GENE= WDHD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7l OCA], [https://pdbe.org/2d7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d7l RCSB], [https://www.ebi.ac.uk/pdbsum/2d7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d7l ProSAT], [https://www.topsan.org/Proteins/RSGI/2d7l TOPSAN]</span></td></tr>
-
|DOMAIN=
+
</table>
-
|RELATEDENTRY=
+
== Function ==
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7l OCA], [http://www.ebi.ac.uk/pdbsum/2d7l PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2d7l RCSB]</span>
+
[https://www.uniprot.org/uniprot/WDHD1_HUMAN WDHD1_HUMAN] Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.<ref>PMID:19805216</ref>
-
}}
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
'''Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1'''
+
Check<jmol>
-
 
+
<jmolCheckbox>
-
 
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d7/2d7l_consurf.spt"</scriptWhenChecked>
-
==About this Structure==
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
2D7L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7L OCA].
+
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d7l ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Inoue, M.]]
+
[[Category: Inoue M]]
-
[[Category: Kamatari, Y O.]]
+
[[Category: Kamatari YO]]
-
[[Category: Kigawa, T.]]
+
[[Category: Kigawa T]]
-
[[Category: Koshiba, S.]]
+
[[Category: Koshiba S]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Saito K]]
-
[[Category: Saito, K.]]
+
[[Category: Tomizawa T]]
-
[[Category: Tomizawa, T.]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S.]]
+
-
[[Category: dna binding]]
+
-
[[Category: helix-turn-helix]]
+
-
[[Category: high mobility group box domain]]
+
-
[[Category: national project on protein structural and functional analyse]]
+
-
[[Category: nppsfa]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:31:03 2008''
+

Current revision

Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1

PDB ID 2d7l

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2d7l"
Personal tools