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6c43

From Proteopedia

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'''Unreleased structure'''
 
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The entry 6c43 is ON HOLD
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==2.9 Angstrom Resolution Crystal Structure of Gamma-Aminobutyraldehyde Dehydrogenase from Salmonella typhimurium.==
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<StructureSection load='6c43' size='340' side='right'caption='[[6c43]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors: Minasov, G., Shuvalova, L., Dubrovska, I., Winsor, J., Tekleab, H., Kwon, K., Anderson, W.F., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6c43]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6C43 FirstGlance]. <br>
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Description: 2.9 Angstrom Resolution Crystal Structure of Gamma-Aminobutyraldehyde Dehydrogenase from Salmonella typhimurium.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6c43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c43 OCA], [https://pdbe.org/6c43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6c43 RCSB], [https://www.ebi.ac.uk/pdbsum/6c43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6c43 ProSAT]</span></td></tr>
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[[Category: Satchell, K.J.F]]
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</table>
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[[Category: Minasov, G]]
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== Function ==
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[[Category: Tekleab, H]]
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[https://www.uniprot.org/uniprot/ABDH_SALTY ABDH_SALTY] Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.[HAMAP-Rule:MF_01275]
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[[Category: Joachimiak, A]]
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__TOC__
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[[Category: Dubrovska, I]]
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</StructureSection>
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[[Category: Anderson, W.F]]
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[[Category: Large Structures]]
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[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
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[[Category: Salmonella enterica]]
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[[Category: Winsor, J]]
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[[Category: Anderson WF]]
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[[Category: Shuvalova, L]]
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[[Category: Dubrovska I]]
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[[Category: Kwon, K]]
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[[Category: Joachimiak A]]
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[[Category: Kwon K]]
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[[Category: Minasov G]]
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[[Category: Satchell KJF]]
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[[Category: Shuvalova L]]
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[[Category: Tekleab H]]
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[[Category: Winsor J]]

Current revision

2.9 Angstrom Resolution Crystal Structure of Gamma-Aminobutyraldehyde Dehydrogenase from Salmonella typhimurium.

PDB ID 6c43

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