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6ffz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of R. ruber ADH-A, mutant F43H, Y54L== | |
| + | <StructureSection load='6ffz' size='340' side='right' caption='[[6ffz]], [[Resolution|resolution]] 1.71Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ffz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._m8 Rhodococcus sp. m8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BKE56_025765 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1925550 Rhodococcus sp. M8])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffz OCA], [http://pdbe.org/6ffz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffz RCSB], [http://www.ebi.ac.uk/pdbsum/6ffz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Laboratory evolution of alcohol dehydrogenase produced enzyme variants with improved turnover numbers with a vicinal 1,2-diol and its corresponding hydroxyketone. Crystal structure and transient kinetics analysis aids in rationalizing the new functions of these variants. | ||
| - | + | Directed Evolution of Alcohol Dehydrogenase for Improved Stereoselective Redox Transformations of 1-Phenylethane-1,2-diol and Its Corresponding Acyloin.,Hamnevik E, Maurer D, Enugala TR, Chu T, Lofgren R, Dobritzsch D, Widersten M Biochemistry. 2018 Feb 2. doi: 10.1021/acs.biochem.8b00055. PMID:29384657<ref>PMID:29384657</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6ffz" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Rhodococcus sp. m8]] | ||
[[Category: Dobritzsch, D]] | [[Category: Dobritzsch, D]] | ||
| + | [[Category: Enugala, T R]] | ||
[[Category: Hamnevik, E]] | [[Category: Hamnevik, E]] | ||
| - | [[Category: Widersten, M]] | ||
| - | [[Category: Enugala, T.R]] | ||
[[Category: Maurer, D]] | [[Category: Maurer, D]] | ||
| + | [[Category: Widersten, M]] | ||
| + | [[Category: Alcohol dehydrogenase mutant variant]] | ||
| + | [[Category: Nadh-dependent]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Rossmann fold]] | ||
| + | [[Category: Zn2+-dependent]] | ||
Current revision
Crystal structure of R. ruber ADH-A, mutant F43H, Y54L
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