5ui1
From Proteopedia
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==Crystal Structure of Human Protein Phosphatase 5C (PP5C) in complex with a triazole inhibitor== | ==Crystal Structure of Human Protein Phosphatase 5C (PP5C) in complex with a triazole inhibitor== | ||
| - | <StructureSection load='5ui1' size='340' side='right' caption='[[5ui1]], [[Resolution|resolution]] 1.96Å' scene=''> | + | <StructureSection load='5ui1' size='340' side='right'caption='[[5ui1]], [[Resolution|resolution]] 1.96Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ui1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UI1 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5ui1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UI1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UI1 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8D4:5-phenyl-1H-1,2,3-triazole-4-carboxylic+acid'>8D4</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8D4:5-phenyl-1H-1,2,3-triazole-4-carboxylic+acid'>8D4</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ui1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ui1 OCA], [https://pdbe.org/5ui1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ui1 RCSB], [https://www.ebi.ac.uk/pdbsum/5ui1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ui1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PPP5_HUMAN PPP5_HUMAN] May play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1. |
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| + | ==See Also== | ||
| + | *[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Banerjee | + | [[Category: Large Structures]] |
| - | [[Category: Chattopadhyay | + | [[Category: Banerjee S]] |
| - | [[Category: Honkanen | + | [[Category: Chattopadhyay D]] |
| - | [[Category: Salter | + | [[Category: Honkanen RE]] |
| - | [[Category: Swingle | + | [[Category: Salter EA]] |
| - | + | [[Category: Swingle MR]] | |
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Current revision
Crystal Structure of Human Protein Phosphatase 5C (PP5C) in complex with a triazole inhibitor
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