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1uob

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==Deacetoxycephalosporin C synthase complexed with 2-oxoglutarate and penicillin G==
==Deacetoxycephalosporin C synthase complexed with 2-oxoglutarate and penicillin G==
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<StructureSection load='1uob' size='340' side='right' caption='[[1uob]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1uob' size='340' side='right'caption='[[1uob]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uob]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UOB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uob]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UOB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dcs|1dcs]], [[1e5h|1e5h]], [[1e5i|1e5i]], [[1hjf|1hjf]], [[1hjg|1hjg]], [[1rxf|1rxf]], [[1rxg|1rxg]], [[1uo9|1uo9]], [[1unb|1unb]], [[1uof|1uof]], [[1uog|1uog]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deacetoxycephalosporin-C_synthase Deacetoxycephalosporin-C synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.20.1 1.14.20.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uob OCA], [https://pdbe.org/1uob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uob RCSB], [https://www.ebi.ac.uk/pdbsum/1uob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uob ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uob OCA], [http://pdbe.org/1uob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uob RCSB], [http://www.ebi.ac.uk/pdbsum/1uob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uob ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CEFE_STRC2 CEFE_STRC2]] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
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[https://www.uniprot.org/uniprot/CEFE_STRCL CEFE_STRCL] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: As 4 1611]]
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[[Category: Large Structures]]
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[[Category: Deacetoxycephalosporin-C synthase]]
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[[Category: Streptomyces clavuligerus]]
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[[Category: Andersson, I]]
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[[Category: Andersson I]]
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[[Category: Dubus, A]]
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[[Category: Dubus A]]
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[[Category: Hajdu, J]]
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[[Category: Hajdu J]]
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[[Category: Oster, L M]]
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[[Category: Oster LM]]
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[[Category: Rhangino, G]]
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[[Category: Rhangino G]]
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[[Category: Scheltinga, A C.Terwisscha van]]
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[[Category: Terwisscha van Scheltinga AC]]
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[[Category: Valegard, K]]
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[[Category: Valegard K]]
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[[Category: Antibiotic biosynthesis]]
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[[Category: Oxidoreductase]]
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Current revision

Deacetoxycephalosporin C synthase complexed with 2-oxoglutarate and penicillin G

PDB ID 1uob

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