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1uzc
From Proteopedia
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==THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11== | ==THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11== | ||
| - | <StructureSection load='1uzc' size='340' side='right' caption='[[1uzc | + | <StructureSection load='1uzc' size='340' side='right'caption='[[1uzc]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1uzc]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1uzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1h40 1h40]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UZC FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uzc OCA], [https://pdbe.org/1uzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uzc RCSB], [https://www.ebi.ac.uk/pdbsum/1uzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uzc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Allen | + | [[Category: Large Structures]] |
| - | [[Category: Bycroft | + | [[Category: Allen MD]] |
| - | [[Category: Friedler | + | [[Category: Bycroft M]] |
| - | [[Category: Jemth | + | [[Category: Friedler A]] |
| - | [[Category: Schon | + | [[Category: Jemth P]] |
| - | + | [[Category: Schon O]] | |
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Current revision
THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11
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Categories: Homo sapiens | Large Structures | Allen MD | Bycroft M | Friedler A | Jemth P | Schon O
